The four-day 2019 Music Biz Conference returned to Nashville for its fifth year this week where music business professionals experienced informative industry panels, hands-on demonstrations of the latest products on the market, and endless networking and professional development opportunities.

More than 47,000 opioid deaths occurred in the United States in 2017, according to the Centers for Disease Control and Prevention (CDC), and for musicians like Dupuis, those losses hit close to home -- which is why some are following Dupuis’ lead by taking Narcan on the road with them.

How can already-major artists take their careers to the next level? Easy: Team up with the masked DJ-producer for an epic collaboration and watch the play counts rack up -- and sometimes eclipse their own biggest hits.

Vampire Weekend is aiming for its third No. 1 album on the Billboard 200 chart with "Father of the Bride."

Plus, moves for Martin Garrix, Oliver Heldens, Madonna & more.