Garth Brooks -- the recipient of this year's icon award -- will also deliver a medley of hits spanning his legendary thirty-plus year career.
Demi Lovato will perform her new song "Commander In Chief," which she released just one day ahead of the event.
Mayor of Atlanta, Keisha Lance Bottoms will present rapper and social activist Killer Mike with the inaugural Billboard Change Maker Award.
Plus, John Legend will perform “Never Break” from his new album Bigger Love.
Post Malone -- who will also perform during the evening -- leads this year's pack of nominees with a grand total of 16 nods in 15 separate categories including top artist (alongside Billie Eilish, Jonas Brothers, Khalid and Taylor Swift), top Billboard 200 album (for Hollywood's Bleeding), top streaming song (for "Sunflower (Spider-Man: Into the Spider-Verse)" with Swae Lee) and more.
The 2020 BBMAs will air Wednesday (Oct. 14) at 8:00 p.m. ET/PT exclusively on NBC, live from the Dolby Theater in Los Angeles.
Check out the complete list of performers and presenters below.
Brandy featuring Ty Dolla Sign
Kelly Clarkson, Pentatonix & Sheila E.
Kane Brown, Swae Lee & Khalid
Post Malone featuring Tyla Yahweh
Mayor of Atlanta Keisha Lance Bottoms
Taraji P. Henson