Mendes shouted out the “brave nurses and doctors out there working so hard every day." He continued: "We’re thinking about you so much. Thank you for everything you’re doing."
Cabello followed up by stating, "We love you, we're in this together, stay safe, stay healthy, stay kind and compassionate with your self and each other. Let’s pull through this together like we always do." And with a strum of Mendes' guitar, the singer jumped into performing "My Oh My."
The stripped-down version highlighted Cabello's delicate falsetto, while also displaying her rap abilities. Since featured guest DaBaby wasn't on hand, Cabello opted to rap his verse by looking at the lyrics on her phone. While Mendes didn't look up much from his guitar, the romantic energy they shared was present.
The iHeart Living Room Concert for America, hosted by Elton John, was an at-home concert special that replaced the 2020 iHeartRadio Music Awards. Other performers included Backstreet Boys, Billie Eilish and Sam Smith.