The tragedy has been classified as a "domestic terror incident" and has rocked the nation and the LGBT community, with many politicians, including Hillary Clinton and Donald Trump, celebrities and public figures swiftly reacting on social media.
Hillary Clinton, Donald Trump React to Orlando Nightclub Mass Shooting
ATX Festival, the annual TV festival in Austin, Texas, canceled a violence-themed panel scheduled for Sunday in the wake of events and the Human Rights Campaign released a statement, saying HRC has lowered its flag to half mast.
Many in Hollywood took to Twitter to react to the news, including Laura Benanti who is currently in rehearsal for tonight's Tony Awards which will be dedicated to victims of the shooting.
This article originally appeared in THR.com.