Strong touched on police shootings by saying that the Secret Service is "the only law enforcement agency in the country that will get in trouble if a black man gets shot."
One joke that didn't get a strong response from the crowd was her reference to Obama's reaction to the Charlie Hebdo attacks: "Paris is so beautiful. Mr. President, you should really think about going there sometime."
Here are five other pointed jokes from her speech.
On Washington sex scandals: "'It is great to be here at the Washington Hilton,' is something a prostitute by say to a Congressman."
On Fox News' demographic: "Fox News has been losing a lot of viewers lately, and may they rest in peace."
On SNL's controversial ISIS skit: "Even us at SNL got criticized this year for making fun of ISIS. I think that's unfair. I mean, if anyone is guilty of taking ISIS too lightly, it's him. [Gestures at Obama.]"
On Brian Williams' controversy: "And what can I say about Brian Williams? Nothing because I work for NBC."
On Hillary Clinton's campaign: "I think she feels the same way Meryl Streep feels when she's asked to audition for something: 'Are you kidding me? You're making me go through this? You know I'm going to win.' "
Her full speech can be seen below.
This article originally appeared in The Hollywood Reporter.