Amy Schumer's MTV Movie Awards Monologue: Watch Her Take on Hillary Clinton & Zayn Malik

Amy Schumer MTV Movie Awards
Kevork Djansezian/MTV1415/Getty Images for MTV

Amy Schumer speaks onstage during The 2015 MTV Movie Awards at Nokia Theatre L.A. Live on April 12, 2015 in Los Angeles, California.

Amy Schumer took a page from Billy Crystal at the Oscars and opened her MTV Movie Awards hosting stint by inserting herself into the year's buzziest movies. Schumer talked with the boy from Boyhood (or at least an 8-year-old stand-in) and the women of Pitch Perfect 2. She got sorted in Divergent, cowered in the face of JK Simmons and even, thanks to Effie Trinket (Elizabeth Banks), got ready for her own Hunger Games. 

MTV Movie Awards 2015: See the Full Winners List

Once on stage, after a purposely uncomfortable dance routine, Schumer opened her monologue with how excited she was to be there. "Half of you don't know who I am, and half of you think I'm Meghan Trainor," she said to laughs. "Pretty psyched about that."

Her monologue gave advice for winners ("I don't want the winners to be worried about speeches going too long, because MTV is the only network that refuses to play music") as well as riffs on Kevin Hart and, a likely big winner this evening, The Fault in Our Stars. Or, as Schumer explained about the weepie blockbuster, "They should have gone with the original title: Cancer Schmancer."

MTV Movie Awards 2015: All the Photos

The best audience reaction to the monologue was a totally-into-it Jennifer Lopez reacting with approval to Schumer's quip about Gone Girl. "How good was Gone Girl?" Schumer asked. "It's the story of what one crazed white woman -- or every Latina -- does when a man cheats on them."

For fans of Inside Amy Schumer and Schumer's comedy in general, she made a couple of just-got-past-the-censors remarks that were sure to delight. Commenting on the excitement for Magic Mike XXL, she remarked, "It really is magic. Whenever I watch those guys, two of my fingers disappear. It's so weird!"

And of course, Schumer had to remark on Hillary Clinton's announcement Sunday afternoon that she'll run for president. "After months of speculation, Hillary Clinton today announced...she's taking Zayn's spot in One Direction," Schumer excitedly announced. "First woman in One Direction: I never thought I'd live to see the day!"

And that's how you bring a news cycle back around.