The special will air at 9 a.m. ET on NBC. Macy's says more than 8,000 people will participate.
Philadelphia Little League baseball team the Taney Dragons will kick off the march with its star pitcher, 13-year-old Mo'ne Davis.
Latin superstar Romeo Santos, Nick Jonas, Miss USA 2014 Nia Sanchez and former NHL players John LeClair and Pat LaFontaine also will take part.
The cast of the Today show will host the three-hour broadcast of the 88th annual Macy's Thanksgiving Day Parade.