Lady Antebellum, LMFAO's Redfoo and SkyBlu, Jason Mraz, Quincy Jones and Glee's Matthew Morrison also will participate.
"The Real Change," produced in association with Adopt a Classroom and sponsor Office Depot, combines celebrities with philanthropy and includes musical performances, interviews and more.
The special will see the musicians -- who will sponsor classrooms -- go back to their hometown schools, introduce the teachers who inspired them and surprise deserving students and organizations.
"Teachers are often the unsung heroes, while actors, musicians and pro athletes get all the praise.
I'm willing to bet, though, that each one of us has had at least one teacher who changed our lives forever," said Liam Murphy, founder and CEO of Real Change Productions. "The goal of our show is to not only honor these teachers but to also inspire Americans to adopt a classroom and support those who are shaping the minds of tomorrow by providing the supplies that enable them to keep making a difference today."
Adopt a Classroom is a group that empowers teachers with the resources they need for their classes and increases their students' chances for success. Teachers can participate by registering on the LiveRealChange.com website. Once they are selected, teachers can use the funds to improve their classrooms.
Real Change Productions is a production and consultant company founded in 2008, focusing on the creative and business sides of TV, film, music and social platforms.