Other previously-announced artists include Mariah Carey, Post Malone and Carrie Underwood.
Performing the genre-bending Latin trap hit "I Like It," the trio will deliver their first performance on the American Music Awards stage. It will also be Cardi's first televised awards show performance since the birth of her daughter Kulture in July.
Cardi B ties for the top-nominated AMAs artist this year with a total of eight nominations, including new artist of the year and favorite rap/hip-hop artist. J Balvin is also nominated for favorite Latin artist.