U2 Pays Tribute to Clarence Clemons in Concert: Watch

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Bono and Adam Clayton of U2 performing live

U2 paid tribute to Clarence Clemons during the Anaheim, Calif. stop of its 360 tour on Saturday night (June 18).

Before launching into "Moment of Surrender," Bono said of the saxophonist, who died earlier that day, "I want you to think about the beautiful symphonic sound that came out of one man's saxophone. I want you to think about Bruce Springsteen and the E Street Band of brothers. I want you to think of Clarence Clemons. This man just carried music, and music carried him, until this day."

Video: U2 pays tribute to Clarence Clemons

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Bono also added several words from the E Street song "Jungleland" into the end of the song.

Clemons died at 69 one week after suffering a stroke at his Florida home. According to reports, he had undergone two brain surgeries while hospitalized but had taken a turn for the worse in recent days.

Known as the "Big Man," Clemons had been with the E Street Band for nearly four decades and helped define the band's sound on such classics as "Born to Run" and "Thunder Road." The 69-year-old underwent two knee replacements and back surgery in the last year; in an interview with Rolling Stone in February, he described his last tour with the band as "pure hell" due to pain.

Most recently, Clemons collaborated with Lady Gaga on her "Born This Way" album, playing sax on the singles "The Edge of Glory" and "Hair" and performing with the pop star on the May 25 "American Idol" season finale. He also appeared in the "Edge of Glory" video, which premiered last Thursday (June 16).

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"Clarence lived a wonderful life," said Springsteen in a statement. "He carried within him a love of people that made them love him. He created a wondrous and extended family. He loved the saxophone, loved our fans and gave everything he had every night he stepped on stage. His loss is immeasurable and we are honored and thankful to have known him and had the opportunity to stand beside him for nearly forty years.

(Additional reporting by Billboard staff)