"I just want you to know that this is really a true love letter to all of you all over the world," she continued, "and I hope a reminder to the kindness that's occurring right now."
World Health Organization and Global Citizen teamed up for the worldwide event, in collaboration with Lady Gaga, in support of healthcare workers in the fight against COVID-19.
"I love you and I hope that you feel a big hug from the whole world today because what's really beautiful about this show is that you're all hugging each other," said the pop star. "Since I was a little girl I always wanted to make people happy, and I didn't know why. But I think I know today."
One World: Together at Home started off with a six-hour stream beginning at 2 p.m. ET. At 8 p.m. ET, a two-hour televised virtual concert -- with scheduled appearances by Gaga, The Rolling Stones, Paul McCartney, Taylor Swift, Billie Eilish and many, many more -- will air. All the performances can be streamed here.
See Gaga's video below.