Madonna Performs 'Rebel Rebel' Tribute to David Bowie: Watch

Neil Lupin/Redferns

Madonna performs during her 'Rebel Heart Tour' at The O2 Arena on Dec. 1, 2015 in London, England. 

Madonna has saluted David Bowie with a performance of his classic song "Rebel Rebel." 

“I want to pay tribute to a man who inspired my career," she told the crowd as her Rebel Heart Tour stopped Tuesday at Houston’s Toyota Arena. “If you haven’t heard of David Bowie, look him up motherf---ers. 

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“He was one of the geniuses in the music industry, one of the greatest singer-songwriters of the 20th century and he changed my life when I went to see him in concert in Detroit. He showed me that it was ok to be different. And he’s the first 'rebel heart' that I laid eyes on.” She then “got the party started” with Bowie’s 1974 standard.

Madonna Remembers David Bowie: 'Talented. Unique. Genius. Game Changer'

Madonna was on hand to induct her good friend and childhood hero into the Rock and Roll Hall of Fame in 1996. When news reached her of Bowie’s death on Jan. 10, a heartbroken Madonna shared three tweets in quick succession. In one of them, she remarked: “Talented . Unique. Genius. Game Changer. The Man who Fell to Earth. Your Spirit Lives on Forever!”

Watch the clip below.