Other performances that stood out include Banda MS' "Que Maldición," Jesse & Joy's inspirational "Love (Es Nuestro Idioma)," and Maluma's angelic performance of "Hawái."
Below, enjoy the top performances of the night:
Performing "Gracias" for the very first time on television, Ozuna returned to the stage for an intimate performance of this track off of his latest album titled ENOC. Surrounded by candles and dressed in angelic white, a thankful Ozuna slowed things down for this stripped-down acoustic track. Making the performance even more special and personal, the superstar's kids joined him onstage. By far one of the most beautiful performances of the night. "Let's take care of our families," Ozuna said. "Let's take care of women. There are too many femicides around the world and they are the ones who gave us life."
See for yourself below.
The awards kicked off with a bang thanks to Maluma, who sang his chart-topping, global hit "Hawái." The Colombian superstar started his performance laying down on a white piano, but he then joined a tribe of dancers onstage to continue singing the reggaetón-pop track.
Reik & Jessie Reyez, “Lo Intenté Todo”
Adding a romantic touch, the Mexican trio and Jessie Reyez took the stage to perform their dreamy collaboration "Lo Intenté Todo" from Reik's EP 20-21. The crowd-pleasing performance marked the first time Reik and Reyez performed onstage together. Reik's frontman Jesús Navarro later returned to the stage to take part in the Armando Manzanero tribute to sing "Como Yo Te Amé."
Banda MS, “Que Maldición”
Taking the stage to perform their chart-topping track "Que Maldición," Banda MS premiered the collab they released with Snoop Dogg earlier this year. While Snoop was not there in person, an animated figure of the Californian rapper appeared on a big screen.
Carlos Vives medley: “Cumbiana,” “La Bicicleta,” “La Gota Fría” and “Pa’ Mayté”
Colombia in the house! Celebrating Carlos Vives' special night -- where he was recognized with the Billboard Hall of Fame Award -- the Colombian star took us down memory lane performing a medley of oldies but goodies, such as "La Gota Fría" and "Pa' Mayté." But before taking us back to the '90s, he performed "Cumbiana," from his most recent album, and the Shakira-assisted "La Bicicleta."
Jesse & Joy, “Love (Es Nuestro Idioma)”
The brother and sister duo took the stage to perform their motivational song "Love (Es Nuestro Idioma)," which was released in June in support of the LGBTQ community and to raise awareness about conversion therapy that is still taking place in Mexico and other parts of the world.
Gente de Zona & Gerardo Ortiz, “Otra Botella”
This trio's performance was one of the night's most highly anticipated performances, and it didn't disappoint. Performing their collaboration for the first time, Gerardo Ortiz and Gente de Zona got everyone on their feet with their mariachi-infused rhythmic track.
Pablo Alborán, "Si Hubieras Querido”
The Spanish singer-songwriter brought light and a touch of intimacy with his performance of the track "Si Huberias Querido." In Alborán fashion, the singer pulled us in as if he was singing to each one of us, whispering his ultra romantic lyrics.
Ozuna, The Black Eyed Peas & J. Rey Soul, “Mamacita”
About an hour into the show, Ozuna and the Black Eyed Peas heated up the stage with their smash hit "Mamacita." Practicing social distancing, Ozuna sang from one stage while Taboo, apl.de.ap and J. Rey Soul danced away to the catchy tune and will.i.am, via augmented reality/artificial intelligence, was in another stage delivering the catchy hook "Mamacita, Mamacita, que bonita."