The rapper's last appearance took place in 2013 when he & Kimmel famously squashed their "beef."
Kanye West will make an appearance on Jimmy Kimmel Live! on Thursday.
Host Jimmy Kimmel made the announcement on Twitter. West's last appearance on Kimmel came in 2013, in what was billed as an attempt to defuse a simmering social media feud between the two stars.
The feud began when West took exception to a Kimmel sketch spoofing the rapper's infamous BBC interview in which he made various outlandish claims and described himself as “the No. 1 rock star on the planet.”