The song is Mendes' first leader and Cabello's second.
As previously reported, Shawn Mendes and Camila Cabello take over atop the Billboard Hot 100 chart with "Señorita," marking Mendes' first trip to No. 1 on the ranking and Cabello's second.
Upon learning the joyous news, Mendes and Cabello shared their reaction with Billboard.
"I'm so excited about the success of 'Señorita,' and thank you so much to our incredible fans who made this all a reality," Mendes said. "We really put everything into this song and couldn't have wished for more."