Willie Nelson, Toby Keith, and Kenny Chesney are among the initial performers confirmed for the 38th annual Academy of Country Music (ACM) Awards show. Set for May 21 at the Mandalay Bay Resort &

Willie Nelson, Toby Keith, and Kenny Chesney are among the initial performers confirmed for the 38th annual Academy of Country Music (ACM) Awards show. Set for May 21 at the Mandalay Bay Resort & Casino in Las Vegas, the event will also feature performances by Brooks & Dunn and Martina McBride. The ceremony will be hosted again this year by Reba McEntire, and will be broadcast live in the U.S. on CBS beginning at 8 p.m. ET.

Chesney is slated to open the broadcast with a performance of his song "Big Star," while Nelson and Keith will team up on their duet "Beer for My Horses." The former is the latest single from Chesney's BNA album "No Shoes, No Shirt, No Problems," which is No. 3 for a second week in a row on Billboard's Hot Country Singles & Tracks chart. "Beer for My Horses" is taken from Keith's latest album, "Unleashed" (DreamWorks) and is currently No. 31 on the country singles tally.

As previously reported, Keith leads the field with eight nominations, followed by Alan Jackson with six, Chesney and Trick Pony with five, and Nelson, Brooks & Dunn, the Dixie Chicks with three.

In addition, Brooks & Dunn, Lonestar, and Wynonna are the nominees for the fan-voted Home Depot Humanitarian Award, which will be presented for the second time. Last year, McEntire was the recipient of the inaugural honor and a HomeDepot/KaBOOM! playground was built in Atoka, Okla., in her name.

More than 78,000 votes have already been cast through the Home Depot Web site, with the poll slated to stay open into the second hour of the CBS telecast. The winner will be announced during the final hour of the ceremony.

ACM Awards show tickets will go on sale April 12 to the public through the Mandalay Bay Resort & Casino (702-632-7580 or 877-632-7400) and through local Ticketmaster outlets. General tickets are prices at $100, with "silver" level tickets running $300 and "gold" level ducats priced at $350.