In keeping with the central theme of focusing global attention on women and girls living with HIV/AIDS, organizers of the South African 46664 benefit concert have confirmed three top female acts for t

In keeping with the central theme of focusing global attention on women and girls living with HIV/AIDS, organizers of the South African 46664 benefit concert have confirmed three top female acts for the event.

Former Eurythmics vocalist Annie Lennox has been tapped to co-headline the March 19 concert, alongside previously announced artists Queen and Paul Rodgers. Joining Lennox is U.K. Katie Melua, whose debut album, "Call off the Search," has reached platinum status in South Africa, according to licensee Just Music. Melua will perform her own material with her band as well as join Queen and Rodgers for part of their set. American R&B artist India.Arie completes the trio.

The artists join an impressive lineup of South African artists that spans the country's diverse music genres, from kwaito to Afro-pop and Afrikaans rock. Among those domestic acts confirmed to appear are Mafikizolo, Kabelo and Mandoza as well as Prime Circle, Kabelo, Danny K, Blk Sonshine and Karen Zoid. Longtime stalwarts of the South African rock scene (now working out of America) Just Jinger are also on the bill, as is Johnny Clegg.

Lennox, who appeared at the first 46664 concert in Cape Town in 2003, is to take on the additional role of spokesperson for the artists appearing and is set to address the audience at the concert.

"It's a real privilege and honor for me to appear once again in South Africa on behalf of the 46664 campaign," she says in a statement. "I am very grateful for the opportunity to lend my voice towards the call for action against this unacceptable genocide, which continues to wipe out millions of men, women and children...not only in Africa, but across the entire globe."

46664 South Africa is being held at the Fancourt Hotel and Country Club Estate in George, a Cape coastal city. It is being underwritten by Fancourt's owner, philanthropist Prof. Dr. Hasso Plattner, who is also donating the venue at no cost.