The show, which had DJ Martin Solveig remixing movie theme songs during show breaks, opened with a performance by Fun., who dressed in matching white suits and sang their hit "We Are Young" with guest Janelle Monae.
Fun.'s set was followed by British comedian Russell Brand's opening monologue, in which he recalled hosting the MTV VMAs when Kanye West infamously interrupted Taylor Swift. He then thanked the rapper's girlfriend Kim Kardashian for taking some of the pressure off of his "short-lived celebrity marriage" to Katy Perry with her even-shorter nuptials. Brand closed his speech by hitting on "Shame" star Michael Fassbender, because, "The last time I did an MTV award show, I did end up marrying someone that was there. So tonight I'm going to keep my eyes peeled for my next wife."
When Wiz Khalifa hit the stage later in the show to perform his latest single, "Work Hard Play Hard," a crowd full of screaming girls waved around empty red solo cups, because that's apparently how they party at major Hollywood awards shows.
Aerosmith stars Steven Tyler and Joe Perry took the stage to present Johnny Depp with the MTV Generation Award, before the actor/guitarist joined the Black Keys to perform their singles "Gold on the Ceiling" and "Lonely Boy." In his acceptance speech, Depp, who's been appearing as a guitarist more and more lately, said he was honored to be onstage with both legends and up-and-coming legends of rock.
Only one music-related award was given out among the movie awards presented to "Hunger Games," "Twilight" and "Harry Potter" -- LMFAO took home the golden popcorn trophy for Best Music, for "Party Rock Anthem" in "21 Jump Street."