Green Day have pulled out of the Voodoo Music Experience, the band announced on Monday.
"Canceling shows is something we rarely do," Tré Cool said in a statement. "We never want to let our fans down, and we are grateful for all of you being understanding during this time."
The group was the first announced headliner for the three-day New Orleans festival, which they'd previously played in 2004. They were slated to perform Oct. 27.
The group postponed a number of promotional appearances after frontman Billie Joe Armstrong's on-stage meltdown at the Las Vegas iHeartRadio Festival in September. He subsequently headed to treatment for substance abuse.
Armstrong's issues haven't derailed the band's releases: "¡Uno!" bowed at No. 2 on the Billboard 200 last week with 139,000 copies sold, second only to Mumford & Sons' juggernaut bow for "Babel." Green Day will also contribute a track to the "Breaking Dawn - Part 2" soundtrack, due Nov. 13.