In one of the most highlight-heavy weeks in the history of the Billboard Hot 100, Lady Gaga roars in at No. 1 with "Born This Way," the 1,000th leader since the list launched in 1958.

Concurrently, with six debuting titles, the "Glee" cast passes Elvis Presley for most Hot 100 chart entries in the chart's more than 52-year archives.

All charts will be refreshed tomorrow (Feb. 17) on Billboard.com.

Lady Gaga Claims 1,000th Hot 100 No. 1

with 'Born This Way'

As previously reported, the milestone "Born This Way," the first single and title track from Lady Gaga's third album, due May 23, fittingly arrives in record-breaking fashion.

On Radio Songs, "Born This Way" begins at No. 6 with a first-week audience of 78.5 million, according to Nielsen BDS. That's the highest bow and largest opening airplay figure for a song since the tally began incorporating all radio formats in December 1998.

Lady Gaga Central

With opening-week digital sales of 448,000, according to Nielsen SoundScan, spurring a No. 1 start on Digital Songs, "Born This Way" logs the largest debut sum for a female artist. Britney Spears established the prior mark four weeks ago upon the arrival of "Hold It Against Me" (411,000).

Notably, "Born This Way" rewrites airplay and digital history after just five days of availability at radio and three days at online retailers.

The 1,000th Hot 100 No. 1 - and just the 19th title to debut at the summit - is Lady Gaga's third chart leader, following her first two singles, "Just Dance," featuring Colby O'Donis, and "Poker Face," both in 2009.

Alongside Gaga's barrier-breaking week, the "Glee" cast bests Presley for most appearances in the Hot 100's history. The ensemble places six debuts on the chart, upping its count to 113 total entries dating to its June 2009 arrival. Presley tallied 108 Hot 100 entries between the survey's inception in 1958 and 2003.

'Glee' Cast Tops Elvis Presley for Most Hot 100 Hits

(The King of Rock and Roll's career predates the Hot 100's launch; Presley scaled numerous Hot 100 predecessor song charts beginning in 1956).

A remake of Katy Perry's recent Hot 100 No. 1 "Firework" represents the "Glee" cast's highest debuting title this week (No. 34), followed by "Silly Love Longs" (No. 45), "When I Get You Alone" (No. 47), "Fat Bottomed Girls" (No. 56), "P.Y.T. (Pretty Young Thing)" (No. 58) and "She's Not There" (No. 87).

Top 10 Artists with the Most Hot 100 Hits

While the first five songs above premiered on the series' Feb. 8 episode, the lattermost track first aired on the "Glee" episode that aired after the Super Bowl Feb. 6. Following a full week of digital sales, three other titles from the Feb. 6 episode advance after debuting on last week's Hot 100: "Thriller / Heads Will Roll" (75-38), "Bills, Bills, Bills" (79-44) and "Need You Now" (72-62).

With nine titles currently on the Hot 100, the "Glee" cast charts its most songs in a single week, besting the eight cuts it placed on the Dec. 18, 2010, chart.

Running down the Hot 100's top 10 below Lady Gaga's landmark launch at No. 1, Perry's original version of "Firework" rebounds 3-2. The song's "Glee" exposure prompts a 40% uptick in digital sales to 170,000.

Bruno Mars' "Grenade" slides 2-3 and Wiz Khalifa's "Black and Yellow" drops 1-4. The latter song and Pittsburgh anthem rose 4-1 last week following the Steelers playoff run to the Super Bowl.

P!nk's "F**kin' Perfect" dips 4-5 on the Hot 100, although it claims Airplay Gainer honors, jumping 16-12 on Radio Songs (68 million in audience, up 22%), and Enrique Iglesias' "Tonight (I'm Lovin' You)," featuring Ludacris and DJ Frank E, holds at No. 6.

Following his Gwyneth Paltrow- and puppet-assisted performance at the 53rd Grammy Awards Sunday (Feb. 13), Cee Lo Green's "F**k You (Forget You)" rockets 16-7, besting its previous peak of No. 9 in December. The song gains on both Digital Songs, where it bounds 12-6 (148,000, up 55%), and Radio Songs, where it rises 23-19 (51 million, up 15%).

Rihanna's "S&M" vaults into the Hot 100's top 10 (33-8) as the chart's Digital Gainer for a second consecutive week, rocketing 20-7 on Digital Songs (145,000, up 93%). The song concurrently charges 57-37 on Radio Songs (30 million, up 33%).

Following the Black Eyed Peas' Super Bowl halftime performance that featured the song, the group's "The Time (Dirty Bit)" rebounds 19-9, fueled by an 11-4 reversal on Digital Songs (153,000, up 46%).

Spears' "Hold It Against Me" rounds out the Hot 100's top 10 (10-10).

In addition to Lady Gaga's No. 1 blastoff and the "Glee" cast's six debuts, other notable new entries belong to Jay Sean, whose "Hit the Lights," featuring Lil Wayne, begins at No. 18; Colbie Caillat, whose "I Do" opens at No. 23; and, Wiz Khalifa, whose "Roll Up," the follow-up to "Black and Yellow," starts at No. 48.