The space-age love song follows "California Gurls," featuring Snoop Dogg, the title cut and "Firework" to the chart's summit, making Perry's second Capitol Records album the first to yield a quartet of Hot 100 No. 1s since Usher's "Confessions" in 2004.
"Teenage Dream" is just the ninth album to produce four No. 1s in the Hot 100's 52-year history. It's the first by a solo female since Mariah Carey's eponymous debut set in 1990-91.
"I am so thrilled that 'E.T.' has landed at No. 1," Perry tells Billboard.com. "I want to thank all the fans who contributed to this amazing feat and radio, which has been an essential part of my continued existence. I truly appreciate all the support of my creative twists and turns."
"Can't wait to share the video with you tomorrow," Perry adds, teasing the premiere of the "E.T." clip at noon ET tomorrow on MTV.com and VEVO.
On Digital Songs, "E.T." spends a third week at No. 1, logging sales of 254,000, according to Nielsen SoundScan. The song concurrently reaches the top 10 on Radio Songs (13-10; 74 million audience impressions, up 35%, according to Nielsen BDS).
"E.T." is Perry's fifth Hot 100 No. 1. Prior to her current album, her 2008 release "One of the Boys" generated the seven-week leader "I Kissed a Girl."
"E.T." marks West's fourth No. 1 and first since "Stronger" in 2007.
The song outpaces Rihanna's "S&M" (3-2) and Cee Lo Green's "F**k You (Forget You)," which rebounds 4-3 after peaking at No. 2 for four weeks. Despite its much-heralded airplay odyssey, due largely to its lyrical content, the latter track reaches the Radio Songs apex (2-1, 111 million in audience, up 7%) in its 18th week on the chart.
Perry's new Hot 100 No. 1 pushes Lady Gaga's "Born This Way" from No. 1 to 4 after spending its first six chart weeks in charge. As previously reported, the first single and title cut from Lady Gaga's new album, due May 23, becomes her record-tying seventh No. 1 on the Pop Songs radio airplay chart.
The Black Eyed Peas' "Just Can't Get Enough" holds at No. 5 on the Hot 100 and Wiz Khalifa's "No Sleep" roars in as the Hot Shot Debut at No. 6. "Sleep" starts at No. 2 on Digital Songs (244,000 downloads). The Pittsburgh rapper, who topped the Hot 100 with his debut smash "Black and Yellow" in February, also claims Digital Gainer honors with "Roll Up," which jumps 45-29 (74,000, up 45%).
Following his heavily-publicized "Good Morning America" appearance last week, Chris Brown rises 8-7 on the Hot 100 with "Look at Me Now," featuring Lil Wayne and Busta Rhymes. The track swaps spots with P!nk's "F**kin' Perfect" (7-8).
As previously reported, Brown scores his first No. 1 on the Billboard 200, as "F.A.M.E." launches atop the album list. Another track from the set, "Next 2 You," featuring Justin Bieber, begins at No. 26 on the Hot 100.
Jeremih's "Down on Me," featuring 50 Cent, pushes 10-9 and Jennifer Lopez's "On the Floor," featuring Pitbull, returns to the top 10 (13-10). The latter title, which peaked at No. 5 for two weeks, climbs 8-7 on Digital Songs (143,000, up 3%) and 42-34 on Radio Songs (33 million, up 24%).
"Floor" concurrently becomes Lopez's sixth consecutive No. 1, and ninth overall, on Billboard's Dance/Club Play Songs chart.